Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1-Reference-Cited by-同舟云学术

Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1

Published:2013-02-14 Issue:7 Volume:121 Page:1229-1237
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Platonova Natalia¹²,Miquel Geraldine¹²,Regenfuss Birgit³,Taouji Said⁴,Cursiefen Claus³,Chevet Eric⁴,Bikfalvi Andreas¹²

Affiliation:

1. Inserm U1029, Talence, France;

2. Université Bordeaux I, Talence, France;

3. Department of Ophthalmology, University of Cologne, Köln, Germany; and

4. Inserm U1053, Team Avenir, Bordeaux, France

Abstract

Key PointsFGF2 is able to directly interact with LYVE-1 and glycosylation of LYVE-1 is important for the interaction with FGF2. LYVE-1 inhibits FGF2-dependent lymphangiogenesis and FGF2 modulates LYVE-1's endogenous expression and reverses the effect of TNFβ.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/7/1229/1368518/zh800713001229.pdf

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