The histone demethylase UTX regulates stem cell migration and hematopoiesis

Author:

Thieme Sebastian1,Gyárfás Tobias1,Richter Cornelia1,Özhan Günes2,Fu Jun2,Alexopoulou Dimitra2,Muders Michael H.3,Michalk Irene4,Jakob Christiane3,Dahl Andreas2,Klink Barbara5,Bandoła Joanna1,Bachmann Michael4,Schröck Evelin5,Buchholz Frank6,Stewart A. Francis27,Weidinger Gilbert8,Anastassiadis Konstantinos27,Brenner Sebastian17

Affiliation:

1. Department of Pediatrics, University Clinic “Carl Gustav Carus” Dresden, Dresden, Germany;

2. BIOTEC, Technische Universitaet Dresden, Dresden, Germany;

3. Department of Pathology and

4. Institute of Immunology, University Clinic “Carl Gustav Carus” Dresden, Dresden, Germany;

5. Institute for Clinical Genetics, Faculty of Medicine “Carl Gustav Carus”, Technische Universitaet Dresden, Dresden, Germany;

6. University Cancer Center, and

7. Center for Regenerative Therapies, Technische Universitaet Dresden, Dresden, Germany; and

8. Institute for Biochemistry and Molecular Biology, Ulm University, Ulm, Germany

Abstract

Key Points UTX regulates migration and hematopoiesis. Female UTX-KO mice show key features of myelodysplastic syndrome with chromosomal instability.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3