Outcomes of hematopoietic cell transplantation using donors or recipients with inherited chromosomally integrated HHV-6-Reference-Cited by-同舟云学术

Outcomes of hematopoietic cell transplantation using donors or recipients with inherited chromosomally integrated HHV-6

Published:2017-08-24 Issue:8 Volume:130 Page:1062-1069
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Hill Joshua A.¹²,Magaret Amalia S.²³⁴,Hall-Sedlak Ruth³,Mikhaylova Anna⁴,Huang Meei-Li³,Sandmaier Brenda M.¹⁵,Hansen John A.¹⁵,Jerome Keith R.²³,Zerr Danielle M.¹⁶,Boeckh Michael¹²

Affiliation:

1. Department of Medicine, University of Washington, Seattle, WA;

2. Vaccine and Infectious Disease, Fred Hutchinson Cancer Research Center, Seattle, WA;

3. Department of Laboratory Medicine and

4. Department of Biostatistics, University of Washington, Seattle, WA;

5. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and

6. Department of Pediatrics, University of Washington, Seattle, WA

Abstract

Key Points Inherited ciHHV-6 was detected in 1.4% of HCT recipients and 0.9% of their donors. Acute GVHD grades 2-4 and cytomegalovirus viremia were more frequent when recipients or donors had inherited ciHHV-6.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/8/1062/1404637/blood775759.pdf

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3. Human herpesvirus 6 and the nervous system;Hill;Handb Clin Neurol,2014

4. The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro;Arbuckle;Proc Natl Acad Sci USA,2010

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