Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma-Reference-Cited by-同舟云学术

Low expression of hexokinase-2 is associated with false-negative FDG–positron emission tomography in multiple myeloma

Published:2017-07-06 Issue:1 Volume:130 Page:30-34
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Rasche Leo¹,Angtuaco Edgardo²,McDonald James E.²,Buros Amy¹,Stein Caleb¹,Pawlyn Charlotte³,Thanendrarajan Sharmilan¹,Schinke Carolina¹,Samant Rohan²,Yaccoby Shmuel¹,Walker Brian A.¹,Epstein Joshua¹,Zangari Maurizio¹,van Rhee Frits¹,Meissner Tobias⁴,Goldschmidt Hartmut⁵,Hemminki Kari⁶⁷,Houlston Richard³,Barlogie Bart¹,Davies Faith E.¹,Morgan Gareth J.¹,Weinhold Niels¹

Affiliation:

1. Myeloma Institute and

2. Radiology Department, University of Arkansas for Medical Sciences, Little Rock, AR;

3. The Institute of Cancer Research, London, United Kingdom;

4. Department of Molecular and Experimental Medicine, Avera Cancer Institute, Sioux Falls, SD;

5. Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany;

6. Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; and

7. Center for Primary Health Care Research, Lund University, Malmo, Sweden

Abstract

Key Points PET false-negativity was seen in 11% of MM patients. PET false-negativity was associated with low hexokinase-2 expression.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/1/30/1401961/blood774422.pdf

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