The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma-Reference-Cited by-同舟云学术

The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma

Published:2018-07-05 Issue:1 Volume:132 Page:59-66
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Rasche Leo¹,Angtuaco Edgardo J.²,Alpe Terri L.¹,Gershner Grant H.¹,McDonald James E.²,Samant Rohan S.²,Kumar Manoj²,Van Hemert Rudy²,Epstein Joshua¹,Deshpande Shayu¹,Tytarenko Ruslana¹,Yaccoby Shmuel¹,Hillengass Jens³,Thanendrarajan Sharmilan¹,Schinke Carolina¹,van Rhee Frits¹,Zangari Maurizio¹,Walker Brian A.¹,Barlogie Bart¹,Morgan Gareth J.¹,Davies Faith E.¹,Weinhold Niels¹

Affiliation:

1. Myeloma Institute and

2. Radiology Department, University of Arkansas for Medical Sciences, Little Rock, AR; and

3. Roswell Park Comprehensive Cancer Center, Buffalo, NY

Abstract

Key Points The presence of ≥3 large focal lesions is associated with poor outcome in newly diagnosed myeloma patients. The prognostic impact of multiple large focal lesions is independent of R-ISS, GEP70, and extramedullary disease.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/132/1/59/1406764/blood842880.pdf

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