Aberrant CD137 ligand expression induced by GATA6 overexpression promotes tumor progression in cutaneous T-cell lymphoma-Reference-Cited by-同舟云学术

Aberrant CD137 ligand expression induced by GATA6 overexpression promotes tumor progression in cutaneous T-cell lymphoma

Published:2018-11-01 Issue:18 Volume:132 Page:1922-1935
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kamijo Hiroaki¹,Miyagaki Tomomitsu¹^ORCID,Shishido-Takahashi Naomi¹²,Nakajima Rina¹,Oka Tomonori¹,Suga Hiraku¹,Sugaya Makoto¹²^ORCID,Sato Shinichi¹

Affiliation:

1. Department of Dermatology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; and

2. Department of Dermatology, International University of Health and Welfare, Chiba, Japan

Abstract

Key Points Overexpression of GATA6 induces aberrant CD137L expression on tumor cells of CTCL. CD137-CD137L interactions promote cell proliferation and migration in CTCL cells, representing potential therapeutic targets.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/132/18/1922/1470372/blood845834.pdf

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