Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells
Author:
Affiliation:
1. Department of Surgery, University of British Columbia, Vancouver, Canada;
2. Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/109/5/2014/1478783/zh800507002014.pdf
Reference56 articles.
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3. Coombes JL, Robinson NJ, Maloy KJ, Uhlig HH, Powrie F. Regulatory T cells and intestinal homeostasis. Immunol Rev2005; 204:184–194.
4. Shevach EM. Regulatory/suppressor T cells in health and disease. Arthritis Rheum2004; 50:2721–2724.
5. Belkaid Y, Sun CM, Bouladoux N. Parasites and immunoregulatory T cells. Curr Opin Immunol2006; 18:406–412.
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