Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain-Reference-Cited by-同舟云学术

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain

Published:2005-12-22 Issue:1 Volume:107 Page:293-300
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:Blood

Author:

Heidel Florian,Solem Fian K.,Breitenbuecher Frank,Lipka Daniel B.,Kasper Stefan,Thiede M. H.,Brandts Christian,Serve Hubert,Roesel Johannes,Giles Francis,Feldman Eric,Ehninger Gerhard,Schiller Gary J.,Nimer Stephen,Stone Richard M.,Wang Yanfeng,Kindler Thomas,Cohen Pamela S.,Huber Christoph,Fischer Thomas

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference31 articles.

1. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

2. Prognostic Implications of the Presence of FLT3 Mutations in Patients with Acute Myeloid Leukemia

3. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

4. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

5. Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

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