The tumor virus landscape of AIDS-related lymphomas-Reference-Cited by-同舟云学术

The tumor virus landscape of AIDS-related lymphomas

Published:2015-05-14 Issue:20 Volume:125 Page:e14-e22
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Arvey Aaron¹,Ojesina Akinyemi I.²³^ORCID,Pedamallu Chandra Sekhar²³,Ballon Gianna⁴,Jung Joonil²³,Duke Fujiko²³,Leoncini Lorenzo⁵,De Falco Giulia⁵,Bressman Eric⁴,Tam Wayne⁴,Chadburn Amy⁶,Meyerson Matthew²³,Cesarman Ethel⁴^ORCID

Affiliation:

1. Department of Immunology and Microbial Pathogenesis, Memorial Sloan-Kettering Cancer Center, New York, NY;

2. Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA;

3. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;

4. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY;

5. Department of Human Pathology and Oncology, University of Siena, Siena, Italy; and

6. Department of Pathology, Northwestern University, Chicago, IL

Abstract

Key Points We evaluated a cohort of ARL samples for known and novel tumor viruses, revealing the oncogenic herpesvirus EBV as the sole detected infectious agent. Heterogeneous viral gene expression suggests that variable host immunosurveillance of EBV latency may influence lymphomagenesis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/20/e14/1386291/e14.pdf

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