Tonic B-cell receptor signaling in diffuse large B-cell lymphoma-Reference-Cited by-同舟云学术

Tonic B-cell receptor signaling in diffuse large B-cell lymphoma

Published:2017-08-24 Issue:8 Volume:130 Page:995-1006
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Havranek Ondrej¹^ORCID,Xu Jingda¹,Köhrer Stefan²,Wang Zhiqiang¹,Becker Lisa¹,Comer Justin M.¹,Henderson Jared¹,Ma Wencai¹,Man Chun Ma John¹,Westin Jason R.¹,Ghosh Dipanjan¹,Shinners Nicholas¹,Sun Luhong¹,Yi Allen F.¹,Karri Anusha R.¹,Burger Jan A.²,Zal Tomasz³,Davis R. Eric¹⁴^ORCID

Affiliation:

1. Department of Lymphoma and Myeloma,

2. Department of Leukemia,

3. Department of Immunology, and

4. Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Abstract

Key Points The GCB subtype of DLBCL relies exclusively on tonic BCR signaling via CD79A Y188. PTEN protein expression and BCR surface density determine the contribution of tonic BCR signaling to AKT activity in GCB-DLBCL.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/8/995/1404876/blood747303.pdf

Reference59 articles.

1. B lymphocyte antigen receptor signaling: initiation, amplification, and regulation;Packard;F1000Prime Rep,2013

2. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling;Alizadeh;Nature,2000

3. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma;Davis;Nature,2010

4. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma;Wilson;Nat Med,2015

5. Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells;Davis;J Exp Med,2001

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