Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo-Reference-Cited by-同舟云学术

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo

Published:2017-04-06 Issue:14 Volume:129 Page:1991-2001
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Vono Maria¹²^ORCID,Lin Ang¹²^ORCID,Norrby-Teglund Anna³^ORCID,Koup Richard A.⁴,Liang Frank¹²^ORCID,Loré Karin¹²^ORCID

Affiliation:

1. Immunology and Allergy Unit, Department of Medicine Solna,

2. Center for Molecular Medicine, and

3. Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; and

4. Vaccine Research Center, National Institutes of Health, Bethesda, MD

Abstract

Key Points Neutrophils can present cognate antigens to antigen-specific memory CD4+ T cells. MHC-II and costimulatory molecules are induced on neutrophils in the presence of antigen and antigen-specific memory CD4+ T cells.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/14/1991/1399736/blood744441.pdf

Reference60 articles.

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4. Pattern recognition receptor function in neutrophils;Thomas;Trends Immunol,2013

5. Neutrophil-derived proteins: selling cytokines by the pound;Cassatella;Adv Immunol,1999

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