Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation-Reference-Cited by-同舟云学术

Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation

Published:2014-07-31 Issue:5 Volume:124 Page:761-770
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Krejsgaard Thorbjørn¹,Willerslev-Olsen Andreas¹,Lindahl Lise M.²,Bonefeld Charlotte M.¹,Koralov Sergei B.³,Geisler Carsten¹,Wasik Mariusz A.⁴,Gniadecki Robert⁵,Kilian Mogens⁶,Iversen Lars²,Woetmann Anders¹,Odum Niels¹

Affiliation:

1. Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark;

2. Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark;

3. Department of Pathology, New York University School of Medicine, New York, NY;

4. Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA;

5. Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark; and

6. Department of Biomedicine, Aarhus University, Aarhus, Denmark

Abstract

Key PointsStaphylococcal enterotoxins stimulate benign T cells to induce activation of the immunoregulatory Stat3/IL-10 axis in malignant T cells. Colonization with enterotoxin-producing Staphylococcus aureus may promote immune dysregulation in cutaneous T-cell lymphoma.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/5/761/541493/761.pdf

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