Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling-Reference-Cited by-同舟云学术

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling

Published:2012-03-29 Issue:13 Volume:119 Page:3187-3189
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Parrow Nermi L.¹,Gardenghi Sara¹,Ramos Pedro¹,Casu Carla¹,Grady Robert W.¹,Anderson Erik R.²,Shah Yatrik M.³,Li Huihui⁴,Ginzburg Yelena Z.⁴,Fleming Robert E.⁵,Rivella Stefano⁶

Affiliation:

1. Division of Hematology-Oncology, Department of Pediatrics, Children's Cancer and Blood Foundation Laboratories, Weill Cornell Medical College, New York, NY

2. Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI

3. Department of Molecular and Integrative Physiology, Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

4. Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY

5. Department of Pediatrics, Saint Louis University School of Medicine, St Louis, MO

6. Division of Hematology-Oncology, Department of Pediatrics, Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/119/13/3187/1349280/zh801312003187.pdf

Reference9 articles.

1. Beta-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.;Ginzburg;Blood,2011

2. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization.;Nemeth;Science,2004

3. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.;Babitt;Nat Genet,2006

4. Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.;Kautz;Blood,2008

5. A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.;Rivella;Blood,2003

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