Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice-Reference-Cited by-同舟云学术

Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice

Published:2018-02-01 Issue:5 Volume:131 Page:563-572
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Zhou Yuan¹²³,Cai Wei⁴,Zhao Zilong¹²,Hilton Tristan³,Wang Min⁴,Yeon Jason³,Liu Wei¹³,Zhang Fangyi⁵,Shi Fu-Dong¹⁶⁷,Wu Xiaoping³,Thiagarajan Perumal⁸,Li Min⁴,Zhang Jianning¹²,Dong Jing-fei³⁹

Affiliation:

1. Tianjin Institute of Neurology, Tianjin, China;

2. Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China;

3. Bloodworks Research Institute, Seattle, WA;

4. Institute of Pathology, Lanzhou University School of Basic Medical Sciences, Lanzhou, China;

5. Department of Neurosurgery, University of Washington School of Medicine, Seattle, WA;

6. Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China;

7. Department of Neurology, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ;

8. Departments of Pathology and Medicine, Baylor College of Medicine and Center for Translational Research on Inflammatory Diseases, Michael E. DeBakey VA Medical Center, Houston, TX; and

9. Division of Hematology, Department of Medicine, University of Washington, School of Medicine, Seattle, WA

Abstract

Key Points Lactadherin promotes the clearance of circulating microvesicles through phagocytosis. Promoting microvesicle clearance prevents coagulopathy, reduces cerebral edema, and improves neurological function in severe TBI mice.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/5/563/1465796/blood801738.pdf

Reference37 articles.

1. Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses;Heemskerk;Blood,1997

2. Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain;Siljander;Arterioscler Thromb Vasc Biol,2001

3. Role of caspase in a subset of human platelet activation responses;Shcherbina;Blood,1999

4. Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program;Brown;J Biol Chem,2000

5. Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets;Fox;J Biol Chem,1991

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