Bleomycin in older early-stage favorable Hodgkin lymphoma patients: analysis of the German Hodgkin Study Group (GHSG) HD10 and HD13 trials

Author:

Böll Boris1,Goergen Helen1,Behringer Karolin1,Bröckelmann Paul J.1,Hitz Felicitas2,Kerkhoff Andrea3,Greil Richard4,von Tresckow Bastian1,Eichenauer Dennis A.1,Bürkle Carolin1,Borchmann Sven1,Fuchs Michael1,Diehl Volker1,Engert Andreas1,Borchmann Peter1

Affiliation:

1. German Hodgkin Study Group, First Department of Internal Medicine, University Hospital Cologne, Cologne, Germany;

2. Cantonal Hospital of St Gallen, St Gallen, Switzerland, and Swiss Group for Clinical Cancer Research, Bern, Switzerland;

3. University Hospital Münster, Münster, Germany; and

4. Third Medical Department, Paracelcus Medical University, Salzburg, Austria

Abstract

Key Points Two cycles of ABVD or AVD were equally tolerable in older early-stage favorable HL patients. Excessive toxicity including severe bleomycin-induced lung toxicity occurred in older HL patients receiving 4 cycles of ABVD.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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