Risk factors predictive of occult cancer detection in patients with unprovoked venous thromboembolism

Author:

Ihaddadene Ryma12,Corsi Daniel J.2,Lazo-Langner Alejandro34,Shivakumar Sudeep56,Zarychanski Ryan78,Tagalakis Vicky910,Solymoss Susan1112,Routhier Nathalie1314,Douketis James1516,Le Gal Gregoire1217,Carrier Marc1217

Affiliation:

1. Department of Medicine, University of Ottawa, Ottawa, ON, Canada;

2. Ottawa Hospital Research Institute, Ottawa, ON, Canada;

3. Department of Medicine, and

4. Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON, Canada;

5. Department of Hematology, Queen Elizabeth II Health Sciences Centre, Halifax, NS, Canada;

6. Department of Medicine, Dalhousie University, Halifax, NS, Canada;

7. Department of Medicine, University of Manitoba, Winnipeg, MB, Canada;

8. Department of Hematology and Medical Oncology, CancerCare Manitoba, Winnipeg, MB, Canada;

9. Department of Medicine, Sir Mortimer B. Davis Jewish General Hospital, Montreal, QC, Canada;

10. Center for Clinical Epidemiology, Lady Davis Institute, Montreal, QC, Canada;

11. Department of Medicine, McGill University, Montreal, QC, Canada;

12. Division of Hematology, Montreal General Hospital and St. Mary’s Hospital, Montreal, QC, Canada;

13. Department of Medicine, Université de Montréal, Montreal, QC, Canada;

14. Sacre Coeur Hospital, Montreal, QC, Canada;

15. St. Joseph’s Healthcare Hamilton, Hamilton, ON, Canada;

16. Department of Medicine, McMaster University, Hamilton, ON, Canada; and

17. The Ottawa Hospital, Ottawa, ON, Canada

Abstract

Key Points It remains unclear whether a subgroup of high-risk patients could potentially benefit from a more extensive screening strategy. Age, prior provoked VTE, and smoking status may be important predictors of occult cancer detection in patients with first unprovoked VTE.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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