Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen–presenting cells
Author:
Affiliation:
1. From the Transplantation Biology Research Center, Bone Marrow Transplantation Section, Massachusetts General Hospital, Harvard Medical School, Boston; and Tufts University School of Veterinary Medicine, North Grafton, MA.
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/100/5/1903/1254762/h81702001903.pdf
Reference26 articles.
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2. Antileukemic effect of chronic graft-versus-host disease.;Weiden;N Engl J Med.,1981
3. Graft-versus-leukemia reactions after bone marrow transplantation.;Horowitz;Blood.,1990
4. Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells.;Sykes;J Exp Med.,1988
5. Lymphohematopoietic graft-vs-host reactions can be induced without graft-vs-host disease in murine mixed chimeras established with a cyclophosphamide-based non-myeloablative conditioning regimen.;Pelot;Biol Blood Marrow Transplant.,1999
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