Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo

Author:

Padrón-Barthe Laura1,Temiño Susana1,Villa del Campo Cristina1,Carramolino Laura1,Isern Joan1,Torres Miguel1

Affiliation:

1. Departamento de Desarrollo y Reparación Cardiovascular, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain

Abstract

Key Points Single cell lineage tracing shows early separation of blood-endothelial precursors in the mouse embryo. Hemogenic endothelium in the YS generates the blood-endothelial common lineage and produces definitive precursors.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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