GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features-Reference-Cited by-同舟云学术

GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features

Published:2014-05-08 Issue:19 Volume:123 Page:3007-3015
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Wang Tianjiao¹,Feldman Andrew L.²,Wada David A.³,Lu Ye¹,Polk Avery¹,Briski Robert¹,Ristow Kay⁴,Habermann Thomas M.⁴,Thomas Dafydd⁵,Ziesmer Steven C.⁴,Wellik Linda E.⁴,Lanigan Thomas M.⁶,Witzig Thomas E.⁴,Pittelkow Mark R.⁷,Bailey Nathanael G.⁵,Hristov Alexandra C.⁵,Lim Megan S.⁵,Ansell Stephen M.⁴,Wilcox Ryan A.¹

Affiliation:

1. Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI;

2. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN;

3. Department of Dermatology, University of Utah, Salt Lake City, UT;

4. Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN;

5. Department of Pathology, and

6. Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI; and

7. Department of Dermatology, Mayo Clinic, Rochester, MN

Abstract

Key Points Alternatively polarized macrophages are abundant constituents of the tumor microenvironment in T-cell lymphoproliferative disorders. GATA-3 expression identifies a subset of PTCL, NOS with a distinct cytokine profile and inferior survival.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/19/3007/1376122/3007.pdf

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