Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial-Reference-Cited by-同舟云学术

Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial

Published:2014-08-07 Issue:6 Volume:124 Page:891-898
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Helton Kathleen J.¹,Adams Robert J.²,Kesler Karen L.³,Lockhart Alex³,Aygun Banu⁴,Driscoll Catherine⁵,Heeney Matthew M.⁶,Jackson Sherron M.²,Krishnamurti Lakshmanan⁷,Miller Scott T.⁸,Sarnaik Sharada A.⁹,Schultz William H.¹⁰,Ware Russell E.¹⁰

Affiliation:

1. St. Jude Children’s Research Hospital, Memphis, TN;

2. Medical University of South Carolina, Charleston, SC;

3. Rho Inc., Chapel Hill, NC;

4. Cohen Children’s Medical Center, New Hyde Park, NY;

5. Montefiore Medical Center, New York, NY;

6. Children’s Hospital Boston, Boston, MA;

7. Pittsburgh Children’s Hospital, Pittsburgh, PA;

8. SUNY-Downstate, Brooklyn, NY;

9. Wayne State University, Detroit, MI; and

10. Cincinnati Children’s Hospital, Cincinnati, OH

Abstract

Key Points Children with SCA and stroke show severe parenchymal and vascular abnormalities that can be assessed using a vasculopathy grading scale. Results from the SWiTCH Trial support concerns about ineffectiveness of transfusion therapy in preventing cerebrovascular injury progression.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/6/891/1382448/891.pdf

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4. Brain imaging findings in pediatric patients with sickle cell disease.;Steen;Radiology,2003

5. Mortality in children and adolescents with sickle cell disease.;Leikin;Pediatrics,1989

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