Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation-Reference-Cited by-同舟云学术

Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation

Published:2015-03-12 Issue:11 Volume:125 Page:1782-1792
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Bartels Marije¹²,Govers Anita M.¹²,Fleskens Veerle¹,Lourenço Ana Rita¹,Pals Cornelieke E.¹,Vervoort Stephin J.¹,van Gent Rogier³,Brenkman Arjan B.⁴,Bierings Marc B.²,Ackerman Steven J.⁵,van Loosdregt Jorg¹²,Coffer Paul J.¹²

Affiliation:

1. Department of Cell Biology, Center for Molecular Medicine, and

2. Division of Pediatrics, University Medical Center Utrecht, Utrecht, The Netherlands;

3. Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands;

4. Department of Metabolic Diseases, University Medical Center Utrecht, Utrecht, The Netherlands; and

5. Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL

Abstract

Key Points C/EBPε acetylation regulates C/EBPε transcriptional activity. C/EBPε acetylation is required for neutrophil differentiation and the formation of neutrophil-specific granules.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/11/1782/1384227/1782.pdf

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