Both platelet- and endothelial cell–derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis-Reference-Cited by-同舟云学术

Both platelet- and endothelial cell–derived ERp5 support thrombus formation in a laser-induced mouse model of thrombosis

Published:2015-04-02 Issue:14 Volume:125 Page:2276-2285
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Passam Freda H.¹²³^ORCID,Lin Lin¹³,Gopal Srila¹³,Stopa Jack D.¹³,Bellido-Martin Lola¹³,Huang Mingdong¹³,Furie Barbara C.¹³,Furie Bruce¹³

Affiliation:

1. Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA;

2. St George Clinical School, University of New South Wales, Sydney, Australia; and

3. Department of Medicine, Harvard Medical School, Boston, MA

Abstract

Key Points ERp5, like its family members PDI and ERp57, accumulates at sites of vessel wall injury. Both platelets and endothelium secrete ERp5 on activation and contribute ERp5 necessary for thrombus formation in vivo.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/14/2276/1384172/2276.pdf

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