Leukofiltration plus pathogen reduction prevents alloimmune platelet refractoriness in a dog transfusion model-Reference-Cited by-同舟云学术

Leukofiltration plus pathogen reduction prevents alloimmune platelet refractoriness in a dog transfusion model

Published:2017-08-24 Issue:8 Volume:130 Page:1052-1061
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Slichter Sherrill J.¹²,Pellham Esther¹,Bailey S. Lawrence¹,Christoffel Todd¹,Gettinger Irena¹,Gaur Lakshmi³,Latchman Yvette⁴,Nelson Karen¹,Bolgiano Doug¹

Affiliation:

1. Bloodworks Northwest, Seattle, WA;

2. Division of Hematology, University of Washington School of Medicine, Seattle, WA;

3. Titan Molecular Laboratories, Seattle, WA; and

4. Etubics Corporation, Seattle, WA

Abstract

Key Points Eight weekly transfusions of F-LR + pathogen-reduced donor platelets were accepted by 31 of 32 (97%) recipient dogs. Among accepting recipients, none developed lymphocyte and only 2 had platelet antibodies not associated with platelet refractoriness.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/8/1052/1404771/blood726901.pdf

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