Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults-Reference-Cited by-同舟云学术

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

Published:2017-02-02 Issue:5 Volume:129 Page:572-581
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Jain Nitin¹,Roberts Kathryn G.²,Jabbour Elias¹,Patel Keyur³,Eterovic Agda Karina⁴,Chen Ken⁴,Zweidler-McKay Patrick⁵,Lu Xinyan³,Fawcett Gloria⁴,Wang Sa A.³,Konoplev Sergej³,Harvey Richard C.⁶,Chen I-Ming⁶,Payne-Turner Debbie²,Valentine Marcus²,Thomas Deborah¹,Garcia-Manero Guillermo¹,Ravandi Farhad¹,Cortes Jorge¹,Kornblau Steven¹,O’Brien Susan⁷,Pierce Sherry¹,Jorgensen Jeffrey³,Shaw Kenna R. Mills⁴,Willman Cheryl L.⁶,Mullighan Charles G.²,Kantarjian Hagop¹,Konopleva Marina¹

Affiliation:

1. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX;

2. Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN;

3. Department of Hematopathology,

4. Institute for Personalized Cancer Therapy, and

5. Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX;

6. Department of Pathology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM; and

7. Division of Hematology/Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA

Abstract

Key Points Approximately 20% to 25% of adults with B-ALL have Ph-like ALL with increased frequency of Ph-like ALL in adults with Hispanic ethnicity. Adult patients with CRLF2+ ALL have poor long-term outcomes; novel strategies are needed to improve the outcomes.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/5/572/1401263/blood726588.pdf

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