DREAM plays an important role in platelet activation and thrombogenesis-Reference-Cited by-同舟云学术

DREAM plays an important role in platelet activation and thrombogenesis

Published:2017-01-12 Issue:2 Volume:129 Page:209-225
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kim Kyungho¹,Tseng Alan¹,Barazia Andrew¹,Italiano Joseph E.²³,Cho Jaehyung¹

Affiliation:

1. Department of Pharmacology, University of Illinois College of Medicine, Chicago, IL;

2. Department of Medicine, Brigham and Women’s Hospital, Boston, MA; and

3. Department of Medicine, Harvard Medical School, Boston, MA

Abstract

Key Points Platelet DREAM is required for platelet thrombus formation at the site of arteriolar injury in mice. Platelet DREAM plays an important role in cell activation by regulation of PI3K class Iβ activity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/2/209/1400810/blood724419.pdf

Reference50 articles.

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2. DREAM is a critical transcriptional repressor for pain modulation;Cheng;Cell,2002

3. Mg2+ and Ca2+ differentially regulate DNA binding and dimerization of DREAM;Osawa;J Biol Chem,2005

4. Calcium-regulated DNA binding and oligomerization of the neuronal calcium-sensing protein, calsenilin/DREAM/KChIP3;Osawa;J Biol Chem,2001

5. Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3;Woo;Neuroreport,2008

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