IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL-Reference-Cited by-同舟云学术

IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL

Published:2013-09-26 Issue:13 Volume:122 Page:2242-2250
ISSN:0006-4971
Container-title:Blood
language:en
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Author:

Nogai Hendrik¹,Wenzel Sören-Sebastian¹²,Hailfinger Stephan³,Grau Michael⁴,Kaergel Eva⁵,Seitz Volkhard⁶,Wollert-Wulf Brigitte¹⁵,Pfeifer Matthias¹,Wolf Annette¹⁷,Frick Mareike¹,Dietze Kerstin¹,Madle Hannelore¹,Tzankov Alexander⁸,Hummel Michael⁶,Dörken Bernd¹⁵,Scheidereit Claus⁵,Janz Martin¹⁵,Lenz Peter⁴,Thome Margot³,Lenz Georg¹

Affiliation:

1. Department of Hematology, Oncology, and Tumor Immunology, Molecular Cancer Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany;

2. Institute for Chemistry and Biochemistry, Freie Universität, Berlin, Germany;

3. Department of Biochemistry, University of Lausanne, Lausanne, Switzerland;

4. Department of Physics, Philipps-University, Marburg, Germany;

5. Max-Delbrück-Center for Molecular Medicine, Berlin, Germany;

6. Institute of Pathology, Charité-Universitätsmedizin Berlin, Berlin, Germany;

7. Institute for Biology, Freie Universität, Berlin, Germany; and

8. Institute of Pathology, University Hospital, Basel, Switzerland

Abstract

Key Points IκB-ζ is essential for nuclear NF-κB activity in ABC DLBCL. ABC DLBCL survival depends on IκB-ζ signaling.

Publisher