High frequency of MYD88 mutations in vitreoretinal B-cell lymphoma: a valuable tool to improve diagnostic yield of vitreous aspirates-Reference-Cited by-同舟云学术

High frequency of MYD88 mutations in vitreoretinal B-cell lymphoma: a valuable tool to improve diagnostic yield of vitreous aspirates

Published:2015-07-02 Issue:1 Volume:126 Page:76-79
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Bonzheim Irina¹,Giese Sabrina¹,Deuter Christoph²,Süsskind Daniela²,Zierhut Manfred²,Waizel Maria³,Szurman Peter³,Federmann Birgit¹,Schmidt Janine¹,Quintanilla-Martinez Leticia¹,Coupland Sarah E.⁴,Bartz-Schmidt Karl Ulrich²,Fend Falko¹

Affiliation:

1. Institute of Pathology and Neuropathology and

2. Centre of Ophthalmology, University Hospital Tübingen, Tübingen, Germany;

3. Department of Ophthalmology, Knappschaftkrankenhaus Saar, Sulzbach, Germany; and

4. Department of Molecular & Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Abstract

Key Points MYD88 mutation analysis significantly improves the detection rate of vitreoretinal B-cell lymphoma. The high frequency of MYD88 mutations in primary VRL provides further evidence that VRL and primary CNS lymphoma represent the same entity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/1/76/1345618/76.pdf

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