AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma

Author:

Noy Ariela1ORCID,Lee Jeannette Y.2,Cesarman Ethel3,Ambinder Richard4,Baiocchi Robert5,Reid Erin6,Ratner Lee7,Wagner-Johnston Nina7,Kaplan Lawrence8

Affiliation:

1. Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical Center, New York, NY;

2. University of Arkansas Medical Center, Little Rock, AR;

3. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY;

4. Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD;

5. Division of Hematology, Ohio State Medical Center, Columbus, OH;

6. University of California San Diego, Moores Cancer Center, La Jolla, CA;

7. Division of Oncology, Washington University School of Medicine, St. Louis, MO; and

8. Department of Medicine, University of California San Francisco, San Francisco, CA

Abstract

Key Points We report the first dedicated prospective study in HIV-Burkitt lymphoma demonstrating safety and efficacy in a multi-institutional setting. We offer a new therapeutic option by modifying an existing regimen and making it much less toxic.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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