Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome-Reference-Cited by-同舟云学术

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome

Published:2016-06-30 Issue:26 Volume:127 Page:3387-3397
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Woollard Wesley J.¹,Pullabhatla Venu²,Lorenc Anna²,Patel Varsha M.¹,Butler Rosie M.¹,Bayega Anthony¹,Begum Nelema¹,Bakr Farrah¹,Dedhia Kiran¹,Fisher Joshua¹,Aguilar-Duran Silvia¹,Flanagan Charlotte¹,Ghasemi Aria A.¹,Hoffmann Ricarda M.¹,Castillo-Mosquera Nubia¹,Nuttall Elisabeth A.¹,Paul Arisa¹,Roberts Ceri A.¹,Solomonidis Emmanouil G.¹,Tarrant Rebecca¹,Yoxall Antoinette¹,Beyers Carl Z.¹,Ferreira Silvia¹,Tosi Isabella¹,Simpson Michael A.³,de Rinaldis Emanuele²,Mitchell Tracey J.¹,Whittaker Sean J.¹

Affiliation:

1. St John’s Institute of Dermatology, Division of Genetics and Molecular Medicine, Tower Wing, King's College London, London, United Kingdom;

2. BRC Bioinformatics Core, Tower Wing, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; and

3. Department of Genetics, Division of Genetics and Molecular Medicine, Tower Wing, King's College London, London, United Kingdom

Abstract

Key Points Aberrations in genome maintenance and DNA repair genes including POT1 occur at a high frequency in Sézary syndrome. Candidate driver genes and affected pathways in Sézary syndrome show extensive heterogeneity but overlap with other mature T-cell lymphomas.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/26/3387/1394329/3387.pdf

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