Plasma biomarkers of acute GVHD and nonrelapse mortality: predictive value of measurements before GVHD onset and treatment-Reference-Cited by-同舟云学术

Plasma biomarkers of acute GVHD and nonrelapse mortality: predictive value of measurements before GVHD onset and treatment

Published:2015-07-02 Issue:1 Volume:126 Page:113-120
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

McDonald George B.¹²^ORCID,Tabellini Laura¹^ORCID,Storer Barry E.¹³,Lawler Richard L.¹,Martin Paul J.¹²^ORCID,Hansen John A.¹²^ORCID

Affiliation:

1. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA; and

2. Department of Medicine, and

3. Department of Biostatistics, University of Washington School of Medicine, Seattle, WA

Abstract

Key Points Before GVHD treatment, informative plasma biomarkers included TIM3, IL6, sTNFR1 (for grade 3-4 GVHD), and ST2 and sTNFR1 (for NRM at 1 year). In a day 14 landmark analysis, plasma TIM3 was predictive of grade 3-4 GVHD.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/1/113/1345147/113.pdf

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