The effect of long-term ruxolitinib treatment on JAK2p.V617F allele burden in patients with myelofibrosis
Author:
Affiliation:
1. University of Utah Huntsman Cancer Institute, Salt Lake City, UT;
2. Fred Hutchinson Cancer Research Center, Seattle, WA;
3. Incyte Corporation, Wilmington, DE; and
4. The University of Texas, MD Anderson Cancer Center, Houston, TX
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/126/13/1551/1388527/1551.pdf
Reference18 articles.
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2. Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders.;Levine;Nat Rev Cancer,2007
3. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.;Pikman;PLoS Med,2006
4. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.;Scott;N Engl J Med,2007
5. Somatic mutations of calreticulin in myeloproliferative neoplasms.;Klampfl;N Engl J Med,2013
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