CLEC-2 is required for development and maintenance of lymph nodes-Reference-Cited by-同舟云学术

CLEC-2 is required for development and maintenance of lymph nodes

Published:2014-05-15 Issue:20 Volume:123 Page:3200-3207
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Bénézech Cécile¹,Nayar Saba¹,Finney Brenda A.²,Withers David R.¹,Lowe Kate²,Desanti Guillaume E.¹,Marriott Clare L.¹,Watson Steve P.²,Caamaño Jorge H.¹,Buckley Christopher D.¹,Barone Francesca¹

Affiliation:

1. School of Immunity and Infection and

2. Centre for Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

Abstract

Key Points CLEC-2 is necessary for lymphatic cell proliferation and lymph node anlage persistence after birth. Lack of CLEC-2 expression on megakaryocytes and platelets compromises lymph node integrity in adult life.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/20/3200/1377004/3200.pdf

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