Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report

Author:

Tefferi Ayalew1,Cervantes Francisco2,Mesa Ruben3,Passamonti Francesco4,Verstovsek Srdan5,Vannucchi Alessandro M.6,Gotlib Jason7,Dupriez Brigitte8,Pardanani Animesh1,Harrison Claire9,Hoffman Ronald10,Gisslinger Heinz11,Kröger Nicolaus12,Thiele Juergen13,Barbui Tiziano14,Barosi Giovanni15

Affiliation:

1. Mayo Clinic, Rochester, MN;

2. Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain;

3. Mayo Clinic, Scottsdale, AZ;

4. Ospedale di Circolo e Fondazione Macchi, Varese, Italy;

5. MD Anderson Cancer Center, Houston, TX;

6. University of Florence, Florence, Italy;

7. Stanford University School of Medicine, Stanford, CA;

8. Service d'Hématologie Clinique, Centre Hospitalier de Lens, Lens, France;

9. Department of Haematology, St. Thomas Hospital, London, United Kingdom;

10. Mount Sinai School of Medicine, New York, NY;

11. Medical University of Vienna, Vienna, Austria;

12. University Hospital Hamburg-Eppendorf, Hamburg-Eppendorf, Germany;

13. University of Cologne, Cologne, Germany;

14. Division of Hematology and Research Foundation, Ospedale Papa Giovanni XXIII, Bergamo, Italy; and

15. Center for the Study of Myelofibrosis, Biotechnology Research Area, Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico S. Matteo Foundation, Pavia, Italy

Abstract

Key Points Treatment response criteria for MF must capture drug benefit in terms of symptom burden. The current document includes stricter definitions of red cell transfusion need and independence.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference22 articles.

1. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment [letter]. Leukemia.;Barosi,2008

2. New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment.;Cervantes;Blood,2009

3. The burden of fatigue and quality of life in myeloproliferative disorders (MPDs): an international Internet-based survey of 1179 MPD patients.;Mesa;Cancer,2007

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