Identification of a cellular ligand for the natural cytotoxicity receptor NKp44-Reference-Cited by-同舟云学术

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

Published:2013-10-24 Issue:17 Volume:122 Page:2935-2942
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Baychelier Florence¹²,Sennepin Alexis¹²,Ermonval Myriam³,Dorgham Karim¹²,Debré Patrice¹²⁴,Vieillard Vincent¹²

Affiliation:

1. Laboratoire Immunité et Infection, Institut National de la Santé et de la Recherche Médicale, UMR-S945,

2. Laboratoire Immunité et Infection, Pierre and Marie Curie University, UMR-S945,

3. Institut Pasteur, Département de Virologie, and

4. Département d’Immunologie, Assistance Publique – Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Paris, France

Abstract

Key Points The cellular ligand of the NKp44L is a novel isoform of the mixed-lineage leukemia-5 protein. NKp44L is not expressed on healthy cells, but on tumor and transformed cells, rendering them more sensitive for the NK cytotoxicity.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/17/2935/1369700/2935.pdf

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