Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B-Reference-Cited by-同舟云学术

Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B

Published:2013-10-03 Issue:14 Volume:122 Page:2346-2357
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Li Jau-Yi¹,Adams Jonathan¹,Calvi Laura M.²,Lane Timothy F.³,Weitzmann M. Neale¹⁴,Pacifici Roberto¹⁵

Affiliation:

1. Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University, Atlanta, GA;

2. Endocrine Division, Department of Medicine, University of Rochester, Rochester, NY;

3. Departments of Obstetrics and Gynecology and Biological Chemistry and Orthopedic Hospital Research Center, University of California, Los Angeles, CA;

4. Atlanta VA Medical Center, Decatur, GA; and

5. Immunology and Molecular Pathogenesis Program, Emory University, Atlanta, GA

Abstract

Key Points Ovariectomy expands short-term hemopoietic stem and progenitor cells and improves engraftment and host survival after bone marrow transplantation. T cells are required for ovariectomy to expand hemopoietic stem and progenitor cells.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/14/2346/1370726/2346.pdf

Reference46 articles.

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4. Ovariectomy augments B lymphopoiesis and generation of monocyte-macrophage precursors in rat bone marrow.;Erben;Am J Physiol,1998

5. Sex steroids and the construction and conservation of the adult skeleton.;Riggs;Endocr Rev,2002

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