X chromosome inactivation analysis reveals a difference in the biology of ET patients with JAK2 and CALR mutations-Reference-Cited by-同舟云学术

X chromosome inactivation analysis reveals a difference in the biology of ET patients with JAK2 and CALR mutations

Published:2014-09-25 Issue:13 Volume:124 Page:2091-2093
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Allen Christopher¹,Lambert Jonathan R.¹,Linch David C.¹,Gale Rosemary E.¹

Affiliation:

1. Department of Haematology, University College London Cancer Institute, London, United Kingdom

Abstract

Key Points In ET, a CALR mutation correlates with a monoclonal X chromosome inactivation pattern, which differs from JAK2V617F mutant disease. The presence of a CALR mutant is associated with suppression of wild-type myelopoiesis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/13/2091/1379558/2091.pdf

Reference23 articles.

1. Clonality analysis of hematopoiesis in essential thrombocythemia: advantages of studying T lymphocytes and platelets.;el-Kassar;Blood,1997

2. A large proportion of patients with a diagnosis of essential thrombocythemia do not have a clonal disorder and may be at lower risk of thrombotic complications.;Harrison;Blood,1999

3. Clonal hemopoiesis and risk of thrombosis in young female patients with essential thrombocythemia.;Chiusolo;Exp Hematol,2001

4. Predictive values of X-chromosome inactivation patterns and clinicohematologic parameters for vascular complications in female patients with essential thrombocythemia.;Shih;Blood,2002

5. Clinical implications of the JAK2 V617F mutation in essential thrombocythemia.;Antonioli;Leukemia,2005

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