Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes-Reference-Cited by-同舟云学术

Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes

Published:2014-12-11 Issue:25 Volume:124 Page:3719-3729
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Weinstein Jason S.¹,Lezon-Geyda Kimberly²,Maksimova Yelena²,Craft Samuel²,Zhang Yaoping²,Su Mack²,Schulz Vincent P.²,Craft Joseph¹³,Gallagher Patrick G.²⁴

Affiliation:

1. Rheumatology Section, Department of Internal Medicine,

2. Department of Pediatrics,

3. Department of Immunobiology, and

4. Departments of Pathology and Genetics, Yale School of Medicine, New Haven, CT

Abstract

Key Points Transcriptomes and enhancers of human CD4+ Tfh and non-Tfh T effector cells reveal cell type–specific differences. These data are a significant resource for understanding mechanisms of normal and perturbed Tfh cell function.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/25/3719/1465011/3719.pdf

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3. Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility.;Weinmann;Immunol Cell Biol,2014

4. The 1-1-1 fallacy.;Crotty;Immunol Rev,2012

5. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.;Johnston;Science,2009

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