A multicenter randomized open-label study of rituximab plus rhTPO vs rituximab in corticosteroid-resistant or relapsed ITP

Author:

Zhou Hai1,Xu Miao1,Qin Ping1,Zhang Hai-yan2,Yuan Cheng-lu3,Zhao Hong-guo4,Cui Zhong-guang4,Meng Yue-sheng5,Wang Lei5,Zhou Fang6,Wang Xin7,Li Da-qi8,Bi Ke-hong9,Zhu Chuan-sheng9,Guo Cheng-shan10,Chu Xiao-xia11,Wu Qing-chao12,Liu Xin-guang1,Dong Xiao-yuan1,Li Jie1,Peng Jun113,Hou Ming113

Affiliation:

1. Department of Hematology, Qilu Hospital, Shandong University, Jinan, China;

2. Department of Hematology, Linyi People's Hospital, Linyi, China;

3. Department of Hematology, Qingdao Central Hospital, Qingdao, China;

4. Department of Hematology, The Affiliated Hospital of Medical College, Qingdao University, Qingdao, China;

5. Department of Hematology, Qingdao Municipal Hospital, Qingdao, China;

6. Department of Hematology, The General Hospital of Jinan Military Commanding Region, Jinan, China;

7. Department of Hematology, Provincial Hospital Affiliated to Shandong University, Jinan, China;

8. Department of Hematology, Shandong University Affiliated Jinan Center Hospital, Jinan, China;

9. Department of Hematology, Qianfoshan Hospital Affiliated to Shandong University, Jinan, China;

10. Department of Hematology, Second Hospital of Shandong University, Jinan, China;

11. Department of Hematology, Yantai Yuhuangding Hospital, Yantai, China;

12. Department of Hematology, Qingdao Haici Hospital, Qingdao, China; and

13. Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, China

Abstract

Key Points Rituximab plus recombinant human thrombopoietin is superior to rituximab monotherapy for corticosteroid-resistant or relapsed ITP patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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