Chromosomal abnormalities in Ph- cells of patients on imatinib-Reference-Cited by-同舟云学术

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Chromosomal abnormalities in Ph- cells of patients on imatinib

Published:2003-10-01 Issue:7 Volume:102 Page:2700-2701
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

McMullin Mary F.,Humphreys Mervyn,Byrne Jenny,Russell Nigel H.,Cuthbert Robert J.,O'Dwyer Michael E.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/102/7/2700/1691287/h81903002695f.pdf

Reference7 articles.

1. O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348: 994-1004.

2. Bumm T, Muller C, Al-Ali H, et al. Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority. Blood. 2003;101: 1941-1949.

3. Andersen MK, Pedersen-Bjergaard J, Kjeldsen L, Dufva IH, Brondum-Neilsen K. Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8. Leukemia. 2002;16: 1390-1395.

4. ME O'Dwyer, KM Gatter, M Loriaux, et al. Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate. Leukemia. 2003;17: 481-487.

5. Wang JY. Regulation of cell death by the Abl tyrosine kinase. Oncogene. 2000;19: 5643-5650.

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5. Transient presence of clonal chromosomal aberrations in Ph-negative cells in patients with chronic myeloid leukemia remaining in deep molecular response on tyrosine kinase inhibitor treatment;Cancer Genetics;2014-10

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