D-dimer to guide the duration of anticoagulation in patients with venous thromboembolism: a management study

Author:

Palareti Gualtiero1,Cosmi Benilde1,Legnani Cristina1,Antonucci Emilia2,De Micheli Valeria3,Ghirarduzzi Angelo4,Poli Daniela2,Testa Sophie5,Tosetto Alberto6,Pengo Vittorio7,Prandoni Paolo8

Affiliation:

1. Angiology and Blood Coagulation, University Hospital of Bologna, Bologna, Italy;

2. Thrombosis Centre, Department Heart and Vessels, University Hospital of Florence, Florence, Italy;

3. Haemostasis and Thrombosis Centre, Hospital of Lecco, Lecco, Italy;

4. Internal Medicine, ASMN-IRCCS-Reggio Emilia, Reggio nell'Emilia, Italy;

5. Haemostasis and Thrombosis Centre, Hospital of Cremona, Cremona, Italy;

6. Haematology and Thrombosis Centre, Hospital of Vicenza, Vicenza, Italy; and

7. Department of Cardiothoracic and Vascular Sciences and

8. Internal Medicine, Department of Medical and Surgical Sciences, University Hospital of Padua, Padua, Italy

Abstract

Key Points The duration of anticoagulation after VTE is uncertain; this management study intended to identify patients with low/high recurrence risk. Patients with persistently negative D-dimers after stopping standard therapy have a low recurrence risk and can stop anticoagulation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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