Inhibition of invariant chain expression in dendritic cells presenting endogenous antigens stimulates CD4+ T-cell responses and tumor immunity
Author:
Affiliation:
1. From the Center for Genetic and Cellular Therapies, Department of Surgery, Duke University Medical Center, Durham, NC.
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/102/12/4137/1692872/h82303004137.pdf
Reference40 articles.
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2. Nair S, Boczkowski D. RNA-transfected dendritic cells. Expert Rev Vaccines. 2002;1: 89-95.
3. Melief CJ, Toes RE, Medema JP, van der Burg SH, Ossendorp F, Offringa R. Strategies for immunotherapy of cancer. Adv Immunol. 2000;75: 235-282.
4. Rosenberg SA. Progress in human tumour immunology and immunotherapy. Nature. 2001;411: 380-384.
5. Pardoll DM, Topalian SL. The role of CD4+ T cell responses in antitumor immunity. Curr Opin Immunol. 1998;10: 588-594.
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