Aged neutrophils contribute to the first line of defense in the acute inflammatory response-Reference-Cited by-同舟云学术

Aged neutrophils contribute to the first line of defense in the acute inflammatory response

Published:2016-11-10 Issue:19 Volume:128 Page:2327-2337
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Uhl Bernd¹^ORCID,Vadlau Yannick¹,Zuchtriegel Gabriele¹²,Nekolla Katharina¹,Sharaf Kariem¹,Gaertner Florian³,Massberg Steffen³,Krombach Fritz¹,Reichel Christoph A.¹²

Affiliation:

1. Walter Brendel Centre of Experimental Medicine,

2. Department of Otorhinolaryngology, Head and Neck Surgery, and

3. Department of Cardiology, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany

Abstract

Key Points Aged neutrophils exhibit a distinct, highly reactive phenotype that depends on age-related changes in their molecular repertoire. This specific phenotype of aged neutrophils enables them to serve as “first responders” in inflammatory reactions.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/19/2327/1396568/2327.pdf

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