Anti-CD45 radioimmunotherapy without TBI before transplantation facilitates persistent haploidentical donor engraftment-Reference-Cited by-同舟云学术

Anti-CD45 radioimmunotherapy without TBI before transplantation facilitates persistent haploidentical donor engraftment

Published:2016-01-21 Issue:3 Volume:127 Page:352-359
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Orozco Johnnie J.¹²,Kenoyer Aimee¹,Balkin Ethan R.³,Gooley Ted A.¹,Hamlin Donald K.³,Wilbur D. Scott³,Hylarides Mark D.¹,Frost Sofia H. L.¹,Mawad Raya¹⁴,O’Donnell Paul¹,Sandmaier Brenda M.¹⁴,Fuchs Ephraim J.⁵,Luznik Leo⁵,Green Damian J.¹⁴,Gopal Ajay K.¹⁴,Press Oliver W.¹⁴,Pagel John M.¹⁴

Affiliation:

1. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA;

2. Hematology Division, Department of Medicine, University of Washington School of Medicine, Seattle, WA;

3. Radiation Oncology, University of Washington, Seattle, WA;

4. Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA; and

5. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD

Abstract

Key Points Anti-CD45 RIT may replace TBI and simplify BMT-preparative regimens. Anti-CD45 RIT and haploidentical BMT, without TBI, prolongs survival in a murine leukemia model.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/3/352/1393420/352.pdf

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4. Race and ethnicity in decisions about unrelated hematopoietic stem cell donation.;Switzer;Blood,2013

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