Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease-Reference-Cited by-同舟云学术

Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease

Published:2015-08-06 Issue:6 Volume:126 Page:703-710
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Detterich Jon A.¹²^ORCID,Kato Roberta M.³,Rabai Miklos⁴,Meiselman Herbert J.²,Coates Thomas D.⁵,Wood John C.¹^ORCID

Affiliation:

1. Division of Cardiology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA;

2. Department of Physiology and Biophysics, University of Southern California Keck School of Medicine, Los Angeles, CA;

3. Division of Pediatric Pulmonology, Children’s Hospital Los Angeles, Los Angeles, CA;

4. Department of Medicine, University of Pecs, Pecs, Hungary; and

5. Division of Hematology, Children’s Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA

Abstract

Key PointsPlasma free hemoglobin is associated with abnormal systemic and pulmonary vascular function markers. Red cell storage time and physical changes in blood are associated with acute transfusional changes in endothelial function.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/6/703/1390904/703.pdf

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