Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study-Reference-Cited by-同舟云学术

Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study

Published:2015-07-30 Issue:5 Volume:126 Page:597-603
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Linkins Lori-Ann¹²,Bates Shannon M.¹²,Lee Agnes Y. Y.³,Heddle Nancy M.¹,Wang Grace¹,Warkentin Theodore E.⁴

Affiliation:

1. Department of Medicine, McMaster University, Hamilton, ON, Canada;

2. Thrombosis & Atherosclerosis Research Institute, Hamilton, ON, Canada;

3. Division of Hematology, University of British Columbia, Vancouver, BC, Canada; and

4. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada

Abstract

Key Points A negative PaGIA test in a patient with low/intermediate 4Ts score excludes HIT with a high level of confidence. A low 4Ts score was insufficient to exclude HIT in some cases because the posttest probability of HIT with a positive PaGIA was moderate.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/5/597/1391586/597.pdf

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3. A 14-year study of heparin-induced thrombocytopenia.;Warkentin;Am J Med,1996

4. Impact of the patient population on the risk for heparin-induced thrombocytopenia.;Warkentin;Blood,2000

5. Rapid detection of heparin-induced platelet antibodies with particle gel immunoassay (ID-HPF4).;Meyer;Lancet,1999

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