Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21–mediated tumor suppressor Pdcd4 repression-Reference-Cited by-同舟云学术

Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21–mediated tumor suppressor Pdcd4 repression

Published:2015-08-20 Issue:8 Volume:126 Page:993-1004
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Junker Fabian¹,Chabloz Antoine¹,Koch Ute¹,Radtke Freddy¹^ORCID

Affiliation:

1. Ecole Polytechnique Fédérale de Lausanne, School of Life Sciences, Swiss Experimental Cancer Research Institute, Lausanne, Switzerland

Abstract

Key Points Dicer1-mediated miRNA biogenesis is essential for induction and maintenance of Notch1-driven T-ALL. miR-21 regulates survival of T-ALL, in part through the repression of the tumor suppressor gene Pdcd4.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/8/993/1391888/993.pdf

Reference65 articles.

1. MicroRNAs: target recognition and regulatory functions.;Bartel;Cell,2009

2. Most mammalian mRNAs are conserved targets of microRNAs.;Friedman;Genome Res,2009

3. Physiological and pathological roles for microRNAs in the immune system.;O’Connell;Nat Rev Immunol,2010

4. Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.;Danen-van Oorschot;Pediatr Blood Cancer,2012

5. MicroRNA miR-125a controls hematopoietic stem cell number.;Guo;Proc Natl Acad Sci USA,2010

Cited by 25 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax;Clinical Epigenetics;2024-03-26

2. Notch Partners in the Long Journey of T-ALL Pathogenesis;International Journal of Molecular Sciences;2023-01-10

3. Flexible and multifaceted: the plasticity of renin-expressing cells;Pflügers Archiv - European Journal of Physiology;2022-05-05

4. MicroRNAs as Modulators of the Immune Response in T-Cell Acute Lymphoblastic Leukemia;International Journal of Molecular Sciences;2022-01-13

5. MicroRNA in leukemia;MicroRNA;2022