Platelets kill circulating parasites of all major Plasmodium species in human malaria-Reference-Cited by-全球学者库

Platelets kill circulating parasites of all major Plasmodium species in human malaria

Published:2018-09-20 Issue:12 Volume:132 Page:1332-1344
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Kho Steven¹,Barber Bridget E.¹²^ORCID,Johar Edison³,Andries Benediktus⁴,Poespoprodjo Jeanne R.⁴⁵⁶,Kenangalem Enny⁴⁵,Piera Kim A.¹,Ehmann Anna³,Price Ric N.¹⁷^ORCID,William Timothy²⁸⁹,Woodberry Tonia¹^ORCID,Foote Simon³^ORCID,Minigo Gabriela¹,Yeo Tsin W.¹²^ORCID,Grigg Matthew J.¹²^ORCID,Anstey Nicholas M.¹²^ORCID,McMorran Brendan J.³^ORCID

Affiliation:

1. Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, NT, Australia;

2. Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit, Kota Kinabalu, Sabah, Malaysia;

3. Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia;

4. Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Papua, Indonesia;

5. Rumah Sakit Umum Daerah Kabupaten Mimika, Timika, Papua, Indonesia;

6. Department of Paediatrics, University of Gadjah Mada, Yogyakarta, Indonesia;

7. Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom;

8. Jesselton Medical Centre, Kota Kinabalu, Sabah, Malaysia; and

9. Clinical Research Centre, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Ministry of Health, Malaysia

Abstract

Key Points Platelets directly interact with and kill circulating Plasmodium parasites in patients with malaria to help control parasitemia. In vitro platelet antiplasmodicidal activity against P knowlesi involves platelet–cell binding and intracellular accumulation of PF4.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/132/12/1332/1467366/blood849307.pdf

Reference68 articles.

1. Platelets and the immune continuum;Semple;Nat Rev Immunol,2011

2. Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines;Krijgsveld;J Biol Chem,2000

3. Antimicrobial peptides from human platelets;Tang;Infect Immun,2002

4. Platelets mediate host defense against Staphylococcus aureus through direct bactericidal activity and by enhancing macrophage activities;Ali;J Immunol,2017

5. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood;Clark;Nat Med,2007

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