ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis

Author:

Branch Donald R.123,Hellberg Åsa45,Bruggeman Christine W.6,Storry Jill R.45,Sakac Darinka3,Blacquiere Megan3,Tong Tik Nga23,Burke-Murphy Emeralda3,Binnington Beth3,Parmar Nagina7,Riden Lorna Sampson7,Willie Kezia7,Armali Chantal8,Aziz Jiwajee9,Lieberman Lani27,Laroche Vincent10,Callum Jeannie28,Lin Yulia28,Shehata Nadine21112,Pavenski Katerina29,Lau Wendy21113,Hannach Barbara12,Kuijpers Taco W.614,Olsson Martin L.45,Cserti-Gazdewich Christine12712,Pendergrast Jacob127

Affiliation:

1. Department of Medicine and

2. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada;

3. Centre for Innovation, Canadian Blood Services, Toronto, ON, Canada;

4. Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden;

5. Department of Clinical Immunology and Transfusion Medicine, Laboratory Medicine, Office of Medical Services, Region Skåne, Lund, Sweden;

6. Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;

7. Laboratory Medicine Program, University Health Network, Toronto, ON, Canada;

8. Department of Clinical Pathology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada;

9. Department of Laboratory Medicine, St. Michael’s Hospital, Toronto, ON, Canada;

10. Institut Universitaire de Cardiologie et Pneumologie de Québec and CHU de Québec and Hôpitaux Enfant-Jésus et Saint-Sacrement, Québec City, QC, Canada;

11. Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada;

12. Canadian Blood Services, Toronto, ON, Canada;

13. Department of Transfusion Medicine, Pediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON, Canada;

14. Pediatric Hematology, Immunology, Rheumatology, and Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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