Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia
Author:
Affiliation:
1. Division of Hematology, Department of Medicine and
2. Department of Molecular Virology, Immunology and Cancer Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH; and
3. Karyopharm Therapeutics, Boston, MA
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/120/9/1765/1363152/zh803512001765.pdf
Reference50 articles.
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3. CRM1-mediated nuclear export of proteins and drug resistance in cancer.;Turner;Curr Med Chem,2008
4. CRM1 is responsible for intracellular transport mediated by the nuclear export signal.;Fukuda;Nature,1997
5. Evidence for a role of CRM1 in signal-mediated nuclear protein export.;Ossareh-Nazari;Science,1997
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