High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysis-Reference-Cited by-同舟云学术

High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysis

Published:2013-10-31 Issue:18 Volume:122 Page:3220-3229
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Fürst Daniel¹²,Müller Carlheinz³⁴,Vucinic Vladan⁵,Bunjes Donald⁶,Herr Wolfgang⁷,Gramatzki Martin⁸,Schwerdtfeger Rainer⁹,Arnold Renate¹⁰,Einsele Hermann¹¹,Wulf Gerald¹²,Pfreundschuh Michael¹³,Glass Bertram¹⁴,Schrezenmeier Hubert¹²,Schwarz Klaus¹²,Mytilineos Joannis¹²⁴

Affiliation:

1. Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttemberg–Hessen, and

2. Institute of Transfusion Medicine, University of Ulm, Ulm, Germany;

3. Zentrales Knochenmarkspender-Register für Deutschland, Ulm, Germany;

4. Deutsches Register für Stammzelltransplantationen (DRST), Ulm, Germany;

5. Department of Hematology/Oncology, University of Leipzig, Leipzig, Germany;

6. Department of Internal Medicine III, University of Ulm, Ulm, Germany;

7. Department of Medicine III, Johannes Gutenberg-University Mainz, Mainz, Germany;

8. Division of Stem Cell Transplantation and Immunotherapy, 2nd Department of Medicine, University of Kiel, Kiel, Germany;

9. Centre for Bone Marrow and Blood Stem Cell Transplantation, Deutsche Klinik für Diagnostik, Wiesbaden, Germany;

10. Hematology/Oncology Department, Charité Campus Virchow Berlin, Berlin, Germany;

11. Department of Medicine II, University Hospital Würzburg, Würzburg, Germany;

12. Department of Hematology/Oncology, Georg-August-University Göttingen, Göttingen, Germany;

13. Department Internal Medicine I, Universitätsklinikum des Saarlandes, Homburg, Germany; and

14. Department of Hematology/Oncology, Asklepios Klinik St. Georg, Hamburg, Germany

Abstract

Key Points HLA mismatches at the allele and antigen level (possibly with the exception of HLA-DQB1) should be treated equally in donor selection. HLA mismatches at >1 locus (including HLA-DQB1) have additive detrimental effects.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/18/3220/1370949/3220.pdf

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4. Trends of hematopoietic stem cell transplantation in the third millennium.;Gratwohl;Curr Opin Hematol,2009

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